Currently, there are some reports concerning adverse pregnancy outcome complicated by anticardiolipin antibody. This study sought to determine the correlation with pregnancy outcome in 62 complicated pregnancies of third trimester of gestation.
Result
were compared with 60 normal pregnancies of third trimester. Sixty-two complicated pregnancy were classified by 52 present complicated pregnancies, 5 previous and 5 previous with present complicated pregnancies. Complicated pregnancies were
combined
with spontaneous abortion more than two, fetal death in uterus after 20 weeks of gestation (FDIU), fetal growth retardation in uterus (IUGR), preterm labor, pregnancy induced hypertension, abruptio placenta and placenta previa. Anticardiolipin
antibody
was detected by enzyme-linked immunosorbent assay (ELISA). Mean level of anticardiolipin antibody was 0.177 in normal pregnancies, 0.127 in previous complicated pregnancies and 0.186 in previous with present complicated pregnancies. Level of
anticardiolipin antibody was not statistically correlated with previous and previous with present complicated pregnancies. In present complicated pregnancies, mean level of anticardiolipin antibody was 0.146, which was statistically significant
association with present complication, especially preterm labor and fetal growth retardation in uterus. On the basis of the above data, we concluded that there is a statistically significant association between level of anticardiolipin antibody
and
the
present complication, especially preterm labor and IUGR. But it is controversal that anticardiolipin antibody seems to be predictive value of complicated pregnancy.
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